Introduction
SCISPARC LTD (NASDAQ: SPRC) is a clinical-stage pharmaceutical company based in Tel Aviv, Israel. The company develops therapies centered on the endocannabinoid system, with applications for conditions including Tourette syndrome, obstructive sleep apnea, Alzheimerās disease, autism spectrum disorder, agitation, status epilepticus, and chronic pain. As of September 30, 2025, SCISPARC shares closed at $5.8608, reflecting an increase of 31.41 percent on a volume of 3,088,573 traded shares.
Corporate Structure
SCISPARC operates with a team of 11ā50 employees and is guided by senior executives with backgrounds in biochemistry, pharmacology, clinical development, and finance. Chairman Itschak Shrem has over 40 years of experience in venture capital and capital markets. Oz Adler serves as Chief Executive Officer and Chief Financial Officer, having previously worked as a CPA at an Ernst & Young affiliate. Dr. Esther Zuloff-Shani, Chief Technologies Officer, has over two decades of experience in research and development, including time at Nasdaq-listed Macrocure Ltd. The scientific advisory board is chaired by Professor Raphael Mechoulam, known for his work in cannabinoid research.

Cannabinoid therapy by Buzzed Buds
Developments and News
On January 15, 2025, Nasdaq granted SCISPARC an additional 180-day extensionāuntil July 14, 2025āto regain compliance with the minimum $1.00 bid price rule, with management considering a potential reverse share split.
In a Form 6-K filed on September 25, 2025, SCISPARC announced a āQuantum Computing-Enabled 3D Protein Modeling Initiativeā aimed at enhancing AI-driven drug discovery. The filing also detailed a leadership transition on September 21, 2025, where Amitay Weiss was appointed President, and Itschak Shrem became Chairman of the Board.
A Form 6-K dated September 26, 2025, disclosed inducement agreements under which holders of 361,548 warrants to purchase ordinary shares at $11.6172 were offered a reduced exercise price of $3.10. The company expects gross proceeds of approximately $1.12 million, designated for working capital and general corporate purposes, subject to customary closing conditions.
On September 30, 2025, SCISPARC filed a Form 6-K reporting the approval of a merger with its majority-owned subsidiary MitoCareX, which focuses on drug discovery targeting resistant cancers such as pancreatic and non-small cell lung cancer.
Financial and Strategic Analysis
SCISPARCās market capitalization was $6.94 million as of September 26, 2025. Key financial metrics for the trailing twelve months include:
- Revenue of $1.31 million
- Net loss of $6.28 million
- Diluted EPS of ā$22.65
- Total cash of $2.06 million
- Debt/equity ratio of 0.51 percent
Price/Sales and Price/Book ratios were noted at 0.91 and 0.85, respectively. The company reported negative returns on assets (ā42.05 percent) and return on equity (ā80.66 percent), reflecting its clinical-stage status and ongoing research and development expenditures.
SCISPARC's pipeline includes four drug candidates in clinical trials and two in pre-clinical development. The merger with MitoCareX represents a strategic move towards oncology, while the quantum computing initiative aims to enhance drug discovery processes. The inducement of warrant exercises indicates a focus on improving liquidity management.
Market Position and Industry Context
Operating in the biotechnology research sector, SCISPARC is positioned within the niche of cannabinoid-based therapies. Its 52-week share price ranged from $1.75 to $37.59, indicating price volatility common among clinical-stage biotech firms. With a beta of 0.90, the stock's price movements have been somewhat less volatile than the broader market. Institutional activity in Q3 2025 included both additions and reductions by firms such as UBS Group, Renaissance Technologies, and Two Sigma. SCISPARCās compliance extension and capital-raising efforts will be closely monitored by investors assessing its ability to maintain operations and advance its pipeline.
tl;dr
- Nasdaq extended SCISPARCās minimum bid price compliance deadline to July 14, 2025; a reverse split is under consideration.
- On September 25, 2025, the company launched a quantum computingāenabled protein modeling initiative and changed its President and Chairman roles.
- Inducement agreements announced on September 26, 2025, aim to raise $1.12 million by lowering warrant exercise prices to $3.10.
- A merger with oncology-focused subsidiary MitoCareX was approved on September 30, 2025, enhancing SCISPARCās drug-discovery capabilities.