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Small-Cap Stocks Soar as Biotech Leads Market Rally

By ATTN Desk · Editorial oversight: Sean Han

Daily Market Recap – July 29, 2025

The U.S. equity market closed sharply higher on July 29, driven largely by a broad rally in small-cap and micro-cap stocks. Biotech and speculative issuers led the advance, with multiple tickers posting triple-digit percentage gains. Trading activity was unusually heavy in several names, reflecting heightened investor interest in high-volatility plays.

Key Quotes Table

TickerATTN PriceCurrent PriceVolumePrice Change %
SRPT13.6115.9149,665,84916.88%
VWAV6.397.555,181,20618.25%
ZOOZ1.401.936,492,64437.71%
DRRX1.291.8628,830,07144.26%
SLRX0.521.3047,509,200151.09%
STAI0.671.12198,759,32867.39%
SCNI1.061.9828,401,36387.10%
BKKT9.8510.203,574,5513.64%
GTLS198.11200.0011,145,4000.96%
NTHI3.264.482,567,72437.41%
AEHL1.423.696,819,469159.13%
CLS177.53202.179,067,06313.92%
SISI0.140.2180,246,59853.61%
NOTE0.450.576,287,71627.78%
PII50.7557.813,514,51813.95%
CASK0.410.6020,345,46646.53%
HWH0.821.8739,808,861127.33%
GIBO0.060.09447,102,60959.85%
STEM12.6715.62643,74623.27%

Market Trends and Patterns

The session was dominated by significant gains among small- and micro-cap equities, particularly in the biotech, healthcare services and technology-adjacent sectors. Several stocks more than doubled in value, while the broader market saw moderate advances. Volume was heavily skewed toward the speculative names, with SCANTECH AI Systems (STAI) trading nearly 199 million shares and GIBO reaching over 447 million.

By contrast, established mid-caps such as Chart Industries (CLS) and Chartwell Technology (GTLS) recorded single-digit to low-double-digit gains, underscoring a risk-on tone among investors.

Small-cap stocks

Small-cap stocks by Patrick Weissenberger

Notable Movers and Volume Surges

  • Antelope Enterprise Holdings (AEHL) jumped 159.13% on 6.8 million shares following strategic financing updates.
  • Salarius Pharmaceuticals (SLRX) climbed 151.09% with 47.5 million shares changing hands amid merger news.
  • HWH International (HWH) rallied 127.33% on 39.8 million shares after unveiling new ventures.
  • SCINAI Immunotherapeutics (SCNI) gained 87.10% on 28.4 million shares amid a financing prospectus filing.
  • SCANTECH AI Systems (STAI) surged 67.39% on record volume, reflecting investor interest in its AI-driven screening systems.

Meanwhile, BitPay (BKKT) and GATX (GTLS) showed more modest moves, rising 3.64% and 0.96%, respectively.

tl;dr

  • Small-cap and micro-cap stocks led broad gains; multiple tickers doubled or more.
  • Highest-volume names included STAI (198M), GIBO (447M) and SLRX (47.5M).
  • Major winners: AEHL (+159%), SLRX (+151%), HWH (+127%) and SCNI (+87%).
  • Mid-caps CLS and GTLS posted moderate gains of 13.9% and 1.0%.
  • Overall market tone: strong risk appetite, heavy flows into speculative equities.

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