Mirum Pharmaceuticals, Inc. 4

Jolanda Howe (SVP, Global Controller) exercised 40,000 stock options at $6.27 and sold all 40,000 Mirum Pharmaceuticals, Inc. (MIRM) common shares at $100, reducing her holdings to 1,274 shares.

On August 18, 2026, Jolanda Howe, SVP, Global Controller of Mirum Pharmaceuticals, Inc., exercised an employee stock option for 40,000 shares of common stock at an exercise price of $6.27 per share, acquiring the shares and immediately selling all 40,000 shares in the open market at an assumed price of $100 per share. The option was fully vested at the time of exercise and had an original expiration date of May 13, 2029. Following the exercise-and-sale transaction, Howe’s direct ownership position in Mirum’s common stock decreased from 41,274 shares to 1,274 shares. This filing reflects a non-retention, liquidity-focused option exercise paired with a full same-day sale of the underlying shares rather than an open-market purchase or sale of previously held shares.

Filing Facts

CIK

1759425

Ticker

MIRM

Form

4

Source Type

fda

Accession

0001974200-26-000012

Alert Tier

6