IONIS PHARMACEUTICALS INC 4

Insider Spencer R. Berthelsen exercised 8,000 stock options and sold 8,000 Ionis Pharmaceuticals (IONS) common shares on June 15, 2026 under a Rule 10b5-1 plan.

On June 15, 2026, Spencer R. Berthelsen, an insider of Ionis Pharmaceuticals Inc., exercised 8,000 non-qualified stock options at an exercise price of $24.42 per share, acquiring 8,000 shares of common stock, and on the same day sold 8,000 shares of common stock at $73.49 per share under a Rule 10b5-1 trading plan adopted on September 12, 2025. The option exercise was reported as an acquisition and increased his direct common stock holdings to 164,013 shares before the sale; the subsequent market sale reduced his direct holdings to 156,013 shares. The Form 4 also notes 70 shares of common stock held indirectly by his daughter, for which he disclaims beneficial ownership. Based on the sale price, the gross value of the shares sold was approximately $587,920, while the option exercise represented an outlay of about $195,360, and his remaining directly held stake is valued at roughly $11.5 million using the same price reference.

Filing Facts

CIK

874015

Ticker

IONS

Form

4

Source Type

sec

Accession

0000874015-26-000207

Alert Tier

6