IONIS PHARMACEUTICALS INC 4

Patrick R. O'Neil (EVP, CLO & General Counsel) sold 3,069 shares of Ionis Pharmaceuticals Inc. common stock at about $80 per share under a Rule 10b5-1 plan.

On June 26, 2026, Patrick R. O'Neil, EVP, CLO & General Counsel of Ionis Pharmaceuticals Inc., sold 3,069 shares of the company's common stock at an average price of approximately $80.00 per share, for total proceeds of about $245,520. Following this Rule 10b5-1 plan trade, his direct ownership stood at 61,470 shares of common stock. The sale was executed under a pre-established Rule 10b5-1 trading plan adopted on December 8, 2025, which typically indicates a pre-programmed, rather than opportunistic, disposition of shares.

Filing Facts

CIK

874015

Ticker

IONS

Form

4

Source Type

sec

Accession

0000874015-26-000217

Alert Tier

6