IONIS PHARMACEUTICALS INC 4

Director Joseph Loscalzo received stock options for 5,369 shares at $79.19 and 2,301 RSUs in Ionis Pharmaceuticals as part of routine non-employee director compensation.

On July 1, 2026, Ionis Pharmaceuticals non-employee director Joseph Loscalzo received routine equity compensation consisting of a non-qualified stock option for 5,369 shares of common stock at an exercise price of $79.19 per share and a restricted stock unit grant for 2,301 shares, both issued under the company’s 2002 Non-Employee Directors’ Stock Option Plan. The option and RSUs each vest 100% on the earlier of the first anniversary of grant or the next annual stockholder meeting, with no portion vested or exercisable on the grant date. Following these awards, Loscalzo directly holds 7,521 shares of Ionis common stock (including the RSUs), and the grants were sized to cap his 2026 annual equity compensation at a grant date fair value of no more than $400,000 under the company’s director compensation policy.

Filing Facts

CIK

874015

Ticker

IONS

Form

4

Source Type

sec

Accession

0000874015-26-000231

Alert Tier

5