IONIS PHARMACEUTICALS INC 4

Non-employee director Michael J. Yang received stock options for 5,369 shares at $79.19 and 2,301 RSUs of Ionis Pharmaceuticals, Inc. common stock as part of routine director equity compensation.

On July 1, 2026, non-employee director Michael J. Yang received routine equity compensation from Ionis Pharmaceuticals, Inc. consisting of a non-qualified stock option for 5,369 shares of common stock at an exercise price of $79.19 per share and a grant of 2,301 restricted stock units, with both awards structured under the company’s Non-Employee Director Compensation Policy such that his total 2026 director equity compensation does not exceed $400,000 in grant-date fair value under ASC 718. The stock options vest in full on the earlier of the first anniversary of grant or the next annual shareholder meeting, and are not exercisable as of the grant date, while the RSUs vest on the same schedule but delivery of shares has been deferred at Mr. Yang’s election until a later triggering event. Following these grants, Mr. Yang beneficially owns 9,451 shares of Ionis common stock on a direct basis.

Filing Facts

CIK

874015

Ticker

IONS

Form

4

Source Type

sec

Accession

0000874015-26-000232

Alert Tier

5