ARROWHEAD PHARMACEUTICALS, INC. 4

Arrowhead Pharmaceuticals’ Chief Medical Officer James C. Hamilton sold 10,000 shares of common stock at about $75 per share under a 10b5-1 plan.

On April 23, 2026, James C. Hamilton, Chief Medical Officer of Arrowhead Pharmaceuticals, Inc., sold 10,000 shares of the company’s common stock at a weighted average price of approximately $75.00 per share, for total proceeds of about $750,000. The sale was executed under a pre-arranged Rule 10b5-1 trading plan, and occurred in multiple transactions at prices ranging from $75.00 to $75.13. Following this transaction, Hamilton reported beneficial ownership of 226,958 shares of Arrowhead common stock, which figure includes shares underlying previously reported restricted stock units, some of which remain subject to vesting conditions.

Filing Facts

CIK

879407

Ticker

ARWR

Form

4

Source Type

sec

Accession

0001830755-26-000007

Alert Tier

6